2025 Week 13 College Football Best Bets

2025 Week 13 College Football Best Bets

Week 12 in the college football universe had some impactful results for the remainder of the season. Texas fell to Georgia, likely eliminating their playoff hopes. Meanwhile, Oklahoma stunned Alabama by winning in Tuscaloosa to propel them into the playoff picture. Texas A&M had a scare at home before performing the largest comeback in school history. The week 13 schedule does not stack up like last week. Most of the SEC is playing out of conference games. Only two ranked matchups in week 13. But there are still plenty of opportunities for teams to make up ground – or tread water to keep their head above water. Here are my Week 13 college football best bets.

Odds courtesy of DraftKings Sportsbook. Lines are subject to change. Please gamble responsibly and within your means. Gambling problem? Call 1-800-GAMBLER.

More: Week 12 Fantasy Football Rankings (2025)

Week 12: 1-4 (-3.46 units)
Year to Date: 25-32 (-11.82 units)

Charlotte (1-9) vs. #4 Georgia (9-1)

Georgia -43.5; O/U 53.5

Charlotte +43.5 (-108)

Hold your nose on this one, folks. But Kirby Smart 0-15 ATS when his team is favored by 38 or more points. They are coming off a huge win against Texas and have completed SEC play, with a top-15 ranked matchup next week against Georgia Tech. What do they have to play for? For Charlotte, going back to 2021, they have played ten games against Power Four teams. They have not lost any of them by more than 38 points. I expect Georgia to call of the dogs for this one and Charlotte to stay within the number.

Baylor (5-5) vs. Arizona (7-3)

Arizona -6.5; O/U 62.5

Arizona -6.5 (-115)

Baylor has played six bowl teams in their ten games this year. The Bears have given up 40.2 PPG in those games, going 2-4 SU and 1-5 ATS. For Arizona, quarterback Noah Fafita has bounced back after a disappointing 2024 campaign, all without a top-10 pick in receiver Tetairoa McMillan. Baylor relies heavily on quarterback Sawyer Robertson; Arizona has not allowed a 200-yard passer in the last six weeks. The Wildcats rank 7th nationally in passing yards per game allowed (159.5) and 6th in yards per attempt (5.4). They have only allowed eight passing touchdowns this year, while intercepting the opposing quarterback 14 times. I think Arizona shows out on senior day and stomps the Bears.

More: Fantasy Notebook: Target & Snap Share Data from Week 9 (2025)

Michigan State (3-7) vs. Iowa (6-4)

Iowa -16.5; O/U 42.5

Iowa -16.5 (-115)

Aidan Chiles is not playing for the Spartans, and backup Alessio Milivojevic, has played well in his place. However, it is uncertain if he will make his third career start at Iowa, due to him being sacked 12 times the last two weeks. It is senior day in Iowa City, and this Iowa team is better than their 6-4 record indicates. They were leading Iowa State and Indiana at the two-minute timeout, took the lead over Oregon after the two-minute timeout, and had some questionable calls last week against USC. Clearly based off last week, this team has not quit despite the results. Michigan State’s defense is the second worst in the Big Ten, only besting UCLA. Iowa is fourth, only trailing the three Big Ten teams expected to make the College Football Playoff. I think Iowa can route Michigan State to avenge a 12-point loss from last year.

More: 2025 College Football Futures

#18 Michigan (8-2) vs. Maryland (4-6)

Maryland +14; O/U 46.5

Maryland +14 (-108)

Michigan has everything to play for next week against Ohio State. A win could propel them into the playoffs. But now they have another road test in College Park. We saw the Wolverines escape Wrigley last week on a game-winning field goal. The last two years under Sherrone Moore, the Wolverines are 0-3 ATS as a road favorite, losing last year at Illinois, while winning this year at Michigan State by 11 and last week’s game by one. I don’t think this one will be pretty. I’m on Michigan to win, but Maryland to keep it within the number.

Fantasy football

More: 2025 College Football Playoff Landscape

Outright Underdogs (.5 units)

Week 12: 0-3 (-1.50 units)
Year to Date: 17-24 (+2.81 units)
(Friday) North Carolina State vs. Florida State +164

Since Florida State’s run in 2023, the Seminoles are 0-7 on the road, including two outright losses as favorites. North Carolina State is 6-2 in their last eight regular season games played during the week, and 6-3 since 2021 as a home underdog. I’m on the Wolfpack to pull the upset in Raleigh on Friday.

Arkansas @ #17 Texas +270

Arkansas is 0-6 in SEC play, but four of the last five losses have come by a field goal or less. Not to mention, Texas just got kicked in the teeth by Georgia, likely eliminating any hope for the playoffs. How motivated are the Longhorns with A&M on deck? I think Arkansas can pull this upset.

Temple vs. #24 Tulane +275

We have seen the top American team fall in the last few weeks. Now they head to Philadelphia to take on Temple, who is coming off a bye and playing for their bowl lives. I think Temple can pull the upset and cause more chaos across the Group of Six.

What is your favorite 2025 week 13 college football best bets? Let me know on X!

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