2025 Week 11 College Football Best Bets
2025 Week 11 College Football Best Bets
The first full week of November football is finally here. We are in the last month of the regular season. The college football playoff committee revealed their initial rankings. Now, everyone knows where they stand before the last month of the season. Week 11 has three ranked matchups in the committee’s eyes, including a top-10 matchup in the Big 12. Everyone is on upset alert this time of year. Here are my Week 11 college football best bets.
Odds courtesy of DraftKings Sportsbook. Lines are subject to change. Please gamble responsibly and within your means. Gambling problem? Call 1-800-GAMBLER.
More: Week 9 Fantasy Football Rankings (2025)
Week 10: 2-3 (-1.32 units)
Year to Date: 20-27 (-11.20 units)
James Madison (7-1) vs. Marshall (4-4)
Marshall +13.5; O/U 54.5
Over 54.5 (-118)
Since Marshall’s 0-2 start, the Thundering Herd have averaged 41.6 PPG in their last five against FBS opponents. The over has covered in each of those five. JMU has scored at least 50 in their last two games. The Dukes need style points if they want to get atop the Group of Six rankings in the committee’s eyes. But I think Marshall can keep this close and it gets high scoring. I’m on the over in this Sun Belt matchup.
#7 BYU (8-0) vs. #8 Texas Tech (8-1)
Texas Tech -10; O/U 52.5
Over 52.5 (-105)
The matchup of the week in Week 11 comes from Lubbock in this top-10 showdown. The loser will get bounced from the top-10, and you could argue this is a must win for Tech, as a loss could have them on the outside looking in for the Big 12 Championship with two conference losses.
This Texas Tech offense has rolled in Big 12 play, scoring at least 34 in five of six games and averaging 36.3 PPG. The Red Raiders have outscored opponents 83-24 in the second half over their last four games. BYU has averaged just under 33 PPG in their three road contests in conference play. I think this one gets high scoring in Lubbock.
More: 2025 College Football Futures
#3 Texas A&M (8-0) vs. #22 Missouri (6-2)
Missouri +7; O/U 47.5
Over 47.5 (-115)
This matchup lost some luster after Missouri quarterback Beau Pribula was lost for the year with a lower body injury. His backup is true freshman Matt Zollers, who was a four star recruit and 9th ranked quarterback in last year’s class. Coach Eli Drinkwitz has a week off to set up the best gameplan for Zollers’ first start. In their last 13 home games, Missouri is averaging 31 PPG.
For the Aggies, we have a seven game sample size of how they play on the road. The over has cashed in each contest with the average score being 71.6 PPG. Each game has seen at least 50 points be scored; Texas A&M has allowed 34 PPG in those contests and at least 20 in each game. I think this one will be more high scoring than we anticipate, despite a backup quarterback. I’m on the over in this ranked SEC matchup.
#9 Oregon (7-1) vs. #20 Iowa (6-2)
Iowa +6.5; O/U 40.5
Iowa: Team Total Under 16.5 (-110)
I bet against the Hawkeyes in their last ranked matchup, thinking they would not be able to stay within the number against Indiana. While I was wrong on that front, I did hit on one trend: Iowa’s offense struggles against ranked teams.
In the last 11 games against ranked matchups, Iowa has averaged 9.4 PPG. They have scored more than two touchdowns in three of those contests, including the last game against Indiana, when Fernando Mendoza ran 40-yards backwards on the last play of the game for a safety. Since the loss to Indiana, Oregon has allowed just 17 points combined in their last two.
While currently in the college football playoff, the Ducks are not as safe as some believed before Tuesday’s reveal. Factor in weather could be an issue, I think the Hawkeyes continue to struggle in these spots and fail to hit 17 points against Oregon.
More: 2025 College Football Playoff Landscape
Navy (7-1) vs. #10 Notre Dame (6-2)
Notre Dame -26.5; O/U 56.5
Notre Dame -26.5 (-110)
This is a large number to cover, but we have seen Notre Dame take care of business against the triple option teams the last few years. Last year, the Irish beat Navy and Army by 37 and 35 points. In 2023, Notre Dame beat Navy in the opener, 42-3. Some thought the Irish were ranked too high in the initial college football playoff rankings reveal, being the top 2-loss team in the field. They are coming off a stinker against Boston College. I think they bounce back this week against Navy.
More: Fantasy Notebook: Target & Snap Share Data from Week 9 (2025)
Outright Underdogs (.5 units)
Week 10: 2-1 (+1.80 units)
Year to Date: 16-20 (+4.01 units)
Arkansas State vs. Southern Mississippi +154
The Sun Belt is the lone conference remaining with divisions, and this one pits two teams atop the Sun Belt West going at it for the right to take on James Madison in a few weeks. Arkansas State has won their last three games outright as a dog. Let’s see if they make it four against the Golden Eagles.
UCONN vs. Duke +260
How motivated is Duke after knocking off Clemson on the road, in a game that has no effect on the ACC race? UCONN is 3-5 SU as a home underdog. I’m on Jim Mora Jr.’s squad to pull the upset in Storrs.
What is your favorite 2025 week 11 college football best bets? Let me know on X!
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