2025 NFL Week 15 Best Bets

2025 NFL Week 15 Best Bets

With week 14 in the rearview mirror, we are back to 16-game weeks in the NFL. The last month of the season is the final push for some teams to solidify their place in the playoffs. With nine teams already mathematically eliminated from the postseason, the Patriots can become the first to clinch a playoff berth this week. Others, are fighting to put themselves in the best position before their last three games. Here are my week 15 best bets.

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Week 14: 2-1 (+1.00 units)
Year to Date: 34-21-1 (+10.93 units)

Cleveland Browns (3-10) vs. Chicago Bears (9-4)

Chicago -7.5; O/U 38.5

Under 38.5 (-112)

Gametime temperatures will be in the single digits, with the feels like number below zero. Bears’ quarterback Caleb Williams struggled early in last week’s frigid game at Lambeau. Now, he goes up against a Jim Schwartz defense that tends to give teams troubles when they first play. I don’t trust rookie Shedeur Sanders to thrive in these elements, either. I’m on this game to fall well under the lowest point total of the week.

Arizona Cardinals (3-10) vs. Houston Texans (8-5)

Houston -10; O/U 42.5

Under 42.5 (-115)

In the three years with DeMeco Ryans as head coach, the under is 10-3-1 in games played against the NFC. This has cashed in the last four for Houston and six of the last seven this season. The game total for the last four has been an average of 34.3 PPG. Arizona has been able to put up points, but this is the top defense in the league, and the Cardinals will be without multiple playmakers on offense. Michael Wilson has provided a spark with Marvin Harrison Jr. sidelined, but Houston has held the WR1 to 52.3 YPG in the last three. I’m on Houston to win this one handedly, with the total falling under the number.

Indianapolis Colts (8-5) vs. Seattle Seahawks (10-3)

Seattle -13.5; O/U 42.5

Seattle -13.5 (-110)
Indianapolis: Team Total Under 13.5 (-105)

Since the Colts acquired cornerback Sauce Gardner at the trade deadline, the season has gone down the toilet. They are 1-3 since the trade, Gardner suffered a lower body injury, and just lost quarterback Daniel Jones to a torn Achilles last week in Jacksonville. To make matters worse, the normal backup, Anthony Richardson, is out with an eye injury and will not be activated from the IR. His backup, Riley Leonard, who replaced Jones last week, has a knee injury that could keep him out of this game. The Colts are so desperate they brought in Philip Rivers to the practice squad to see if he could help the Colts finish out the season.

I haven’t even touched on the Seahawks and their defense that ranks as one of the best in the league. Seattle is 6th in total yards allowed (288.2 YPG), 4th in rushing yards (91.2 YPG), and 2nd in scoring defense (17.4 PPG). Under the defensive minded Mike McDonald, Seattle is 8-1 (5-3-1 ATS) against the AFC, allowing just 18.6 PPG to healthy teams. This year, the Seahawks are a league best 10-3 ATS. I believe Seattle will win this one in a route.

Carolina Panthers (7-6) vs. New Orleans (3-10)

New Orleans +2.5; O/U 40.5

Over 40.5 (-110)

In the two years with Dave Canales as head coach and Bryce Young under center, the Panthers are 11-13. Against NFC South opponents under the same combination, the Panthers are 4-4 with an average game total of 50.8 PPG; the Panthers average 22.6 PPG. Only two of the eight ell under this point total. For the Saints, rookie Tyler Shough will make his sixth start, where he is 2-3 as a starter. This is his second time against the Panthers, where he had his best start of his young career. I’m on both teams clearing this point total in this NFC South matchup.

Outright Underdogs (.5 Units):
Week 14: 1-1 (+0.07 units)
Year to Date: 5-17 (-5.56 units)
Cleveland @ Chicago +310

I touched on it above, but the elements in this game can make it a weird one. Caleb Williams has yet to win in December (granted, just 0-1 under Ben Johnson). The Bears are 6-2 in one possession games this year. This is the type of game where you can find yourself on the wrong side of that statistic. I believe the Browns can pull the upset.

Los Angeles @ Kansas City  +205

The Chargers have been underdogs seven times under Jim Harbaugh and Justin Herbert. They are 3-4 in those games, and now they play for a chance to sweep the struggling Chiefs. Herbert is 3-7 when squaring off with Mahomes, with two losses coming in overtime. I think the Chargers can knock off Kansas City in this one.

Fantasy football

Miami vs. Pittsburgh +140

Going back to 2017, the Steelers are 3-5 in regular season games immediately following a win over Baltimore. I touched on Pittsburgh last week: just when you think they are out, they will prove you wrong. And as soon as you start to believe, they will let you down again. I think Miami pulls the upset to wrap up the week 15 best bets.

What are some of your favorite week 15 best bets? Let me know on X! Follow me @DrewRoberts_ on X for more football content!

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